Clinical Outcomes Associated With Sickle Cell Trait
نویسندگان
چکیده
منابع مشابه
Sickle-cell trait: novel clinical significance.
There is a long-standing controversy in the literature as to whether sickle-cell trait (SCT) should be viewed as a benign carrier state or as an intermediate disease phenotype. Because SCT is routinely detected by neonatal screening for sickle-cell disease, it becomes imperative that consensus on this issue be achieved in order to provide the best medical advice to affected individuals. The iss...
متن کاملPulmonary infarction in disorders associated with the sickle cell trait.
The disorders associated with the sickle cell trait have not, in the past, been seen very often in Britain because they are largely confined to the Negro race. However, increased immigration from the West Indies, where the trait can be found in about 10% of the Negro population (Tomlinson, 1945), has made the recognition of these diseases more important in this country (Diamond, 1959). The sick...
متن کاملExertional collapse and sudden death associated with sickle cell trait.
The most serious complication of sickle cell trait (SCT) is sudden death during exertion. SCT often remains unrecognized in the 2.5 million African Americans affected. Exertional collapse and sudden death associated with SCT is characterized by rhabdomyolysis, heat stroke, and cardiac arrhythmia. There is a 40-fold increased risk of sudden death in affected soldiers during military basic traini...
متن کاملComplications associated with sickle cell trait: a brief narrative review.
Sickle cell trait occurs in approximately 300 million people worldwide, with the highest prevalence of approximately 30% to 40% in sub-Saharan Africa. Long considered a benign carrier state with relative protection against severe malaria, sickle cell trait occasionally can be associated with significant morbidity and mortality. Sickle cell trait is exclusively associated with rare but often fat...
متن کاملHematuria associated with sickle cell trait during pregnancy.
Although sickle cell trait is usually considered a benign condition, it has frequently been associated with hematuria and an increased incidence of pyelonephritis. This case report highlights the complications that can occur with sickle cell trait in a pregnant patient. Pregnancy enhances the susceptibility for renal problems, and pregnant patients who develop complications require close monito...
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ژورنال
عنوان ژورنال: Annals of Internal Medicine
سال: 2018
ISSN: 0003-4819
DOI: 10.7326/m18-1161